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Bone differs from any other soft tissue since it heals through a process of generation of the new bone rather than by forming fibrotic tissue. Bone repair requires four critical elements: -Osteogenic cells; -Osteoinductive factors provided mainly by growth factors and bone morphogenic proteins; -Osteoconductive matrix. -Adequate blood and nutrients supply. Since 1920 calcium phosphate ceramics have been used as bone substitutes due to its similarity to the mineral part of the natural bone so that they can be recognized, dissolved and remodeled as new bone tissue. This synthetic bone graft substitutes are highly osteoconductive and bioactive, forming a strong bond to the host bone providing the adequate environment for the remodeling process. |
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NeoBone
Presentation:
NeoBone®, is a biphasic synthetic ceramic made of hydroxyapatite (75%) and tricalcium phosphate (25%) with interconnected macroporosity which allows the ingrowth of new bone.
NeoBone® is available in many shapes such as granules, blocks and wedges.
Applications:
NeoBone® is design for filling bone defects.
CE Mark: CE 0434
NeoCement
Presentation:
NeoCement®, is an hydroxyapatite cement composed of a solid phase (tetracalcium phosphate and tricalcium phosphate), a liquid phase in powder form (citric acid and chitosan) and apyrogenic water. The solid and liquid phases are mixed to form a paste that sets in a few minutes.
NeoCement® can be molded in theaste that sets in a few minutes. It can be molded in the desired shaped and applied directly in the bone defect.
NeoCement® is presented in a package with three flasks containing, a solid phase of calcium phosphate powder, a liquid phase in powder form and apryrogenic water.
Applications:
NeoCement® ® is indicated for use in the treatment of small bone defects in craniofacial and trauma surgery.
CE Mark: CE 0434
k-IBS
Presentation:
k-IBS®, is an injectable bone substitute composed of calcium phosphate granules suspended in a polymeric matrix based on chitosan.
k-IBS® is a totally resorbable injectable gel, easy to apply and to mold into the bone defect.
k-IBS® is a ready-to-use injectable bone substitute packaged in a syringe for an easy-to-use application.
Applications:
k-IBS® acts as a temporary osteoconductive scaffold for the ingrowth of viable bone. k-IBS® is not intended to provide structural support.
k-IBS® can be used in applications such as:
·Reconstruction of post traumatic bone defects;
·Periodontal defects filling;
·Cystectomy filling;
·Alveolar bone filling;
·Osteotomies;
·Spinal surgery cages filling;
·Acetabulum reconstruction;
·Metaphysial fractures.
CE Mark: CE 0434
n-IBS
Presentation:
n-IBS® is an injectable bone substitute composed of100% hydroxyapatite nanoparticles.
n-IBS® is totally resorbable injectable bone substitute and enhance bone formation due to its nanocrystalline structure similar to natural bone.
n-IBS® is a ready-to-use injectable bone substitute packaged in a syringe for an easy-to-use application.
Applications:
n-IBS® acts as a temporary osteoconductive scaffold for the ingrowth of viable bone. n-IBS® is not intended to provide structural support.
n-IBS® can be used in applications such as:
·Reconstruction of post traumatic bone defects;
·Periodontal defects filling;
·Cystectomy filling;
·Alveolar bone filling;
·Osteotomies;
·Spinal surgery cages filling;
·Acetabulum reconstruction;
·Metaphysial fractures.
CE Mark: CE 0434
